20
341
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6836 |
FIIN-2
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FIIN2 是一种 FGFR 的不可逆抑制剂,能够抑制 FGFR1 (IC50:3.1 nM),FGFR2 (IC50:4.3 nM),FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。 | |||
T2609 |
Masitinib
AB1010,马赛替尼 |
Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。 | |||
T8492 |
BO-264
|
Apoptosis; FGFR | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
BO-264 是一种有口服活性的转化酸性卷曲螺旋 3 抑制剂,可特异性阻断 FGFR3-TACC3融合蛋白的功能。它诱导纺锤体检查点依赖的有丝分裂阻滞,DNA 损伤和细胞凋亡,具有广谱抗肿瘤活性。 | |||
T24804 |
SM27
SM-27,NSC-37204,SM 27,NSC37204 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
SM27 是一种成纤维细胞生长因子 2(FGF2) 抑制剂,具有抗血管生成活性,可用于研究肿瘤。 | |||
T16781 |
Rogaratinib
BAY1163877 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Rogaratinib (BAY1163877) 选择性抑制成纤维细胞生长因子受体。 | |||
T7104 |
Dovitinib lactate
CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate |
VEGFR; FGFR; FLT; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Dovitinib lactate (TKI-258 lactate) 是一种多靶点的酪氨酸激酶抑制剂,抑制FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和PDGFRα/β的IC50值分别为 1,2,8/9,10/13/8,27/210 nM。 | |||
T3714 |
SUN11602
SUN 11602 |
ERK; FGFR | Angiogenesis; MAPK; Tyrosine Kinase/Adaptors |
SUN11602 是新型的碱性苯胺化合物,具有成纤维细胞生长因子特性。 | |||
T11279 |
FGFR1/DDR2 inhibitor 1
|
Discoidin Domain Receptor (DDR); FGFR; Others | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
FGFR1/DDR2 inhibitor 1 是一种具有口服活性的成纤维细胞生长因子受体 1 和盘状蛋白域受体 2 的抑制剂,能够抑制 FGFR1 (IC50:31.1 nM) 和 DDR2 (IC50:3.2 nM),具有抗肿瘤作用。 | |||
T2160 |
Suramin Sodium Salt
苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060 |
Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K,是抗寄生虫,抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂,也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。 | |||
T28938 |
Tec-IN-14
TecIN14 |
||
Tec-IN-14 is a Tec kinase inhibitor. Tec-IN-14 blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
T28939 |
Tec-IN-21
TecIN21,Tec IN 21,Tec Inhibitor-21 |
||
Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
T28940 |
Tec-IN-6
Tec Inhibitor-6 |
||
Tec-IN-6 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
T25110 |
AS1069562
AS-1069562,AS 1069562 |
||
AS1069562 is an inhibitor of serotonin (5-HT) and norepinephrine (NE) reuptake which acts by notably restoring reduced insulin-like growth factor 1 and fibroblast growth factor 2 mRNA levels in dorsal root ganglion and spinal cord, respectively. | |||
T27234 |
E7090
E-7090,E 7090 |
||
E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3. | |||
T68935 |
BMS-645737
|
||
BMS-645737 is an inhibitor of vascular endothelial growth factor (VEGF) receptor-2 and fibroblast growth factor (FGF) receptor-1. BMS-646737 has anti-angiogenic activity and was evaluated in nonclinical studies as a treatment for cancer. | |||
T78313 |
Fazpilodemab
BFKB8488A |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Fazpilodemab (BFKB8488A) 是靶向 FGFR1c 和 Klothoβ 的激动性人源化双特异性抗体,适用于T2DM或NAFLD的研究。 | |||
T36292 |
NSC 12
|
||
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans (HSPGs). NSC 12 also binds several other, but not all, FGF isoforms with Kd values ranging between 16 and 120 μM, preventing them from forming HSPG/FGF/FGFR ternary complexes. NSC 12 inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduc... | |||
T76277 |
Vosoritide
|
||
Vosoritide (BMN 111) 为改良重组CNP (C型钠尿肽) 类似物,作用于NPR-B (B型钠尿肽受体),能有效降低FGFR3 (成纤维细胞生长因子受体 3) 活性,主要应用于软骨症和侏儒症研究领域。 | |||
T36714 |
Sucrose octasulfate (potassium salt)
|
||
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by pr... | |||
T67442 |
CGP-53716
|
||
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase inhibition has been shown to be effective in blocking tyrosine phosphorylation at the PDGF and bFGF receptors in cultured fibroblast and vascular smooth muscle cells which in turn inhibits their proliferation[1]. CGP 53716 is a specific PDGFR tyrosine kinase inhibitor on SMC (smoo... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00037 |
FGF-2 Protein, Mouse, Recombinant
Fibroblast Growth Factor 2 |
Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari... | |||
TMPJ-00842 |
FGF-2 Protein, Rat, Recombinant
bFGF,Heparin-Binding Growth Factor 2 |
Rat | E. coli |
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g... | |||
TMPY-01061 |
FGF-10 Protein, Human, Recombinant
fibroblast growth factor 10,KGF |
Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla... | |||
TMPY-00210 |
FGF-2 Protein, Mouse, Recombinant (His)
Fgfb,bFGF,Fgf-2,fibroblast growth... |
Mouse | E. coli |
FGF-2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.5 kDa and the accession number is P15655. | |||
TMPY-03382 |
FGF-6 Protein, Human, Recombinant
HBGF-6,HST2,fibroblast growth |
Human | E. coli |
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene d... | |||
TMPY-00749 |
FGF-2 Protein, Human, Recombinant
fibroblast growth factor 2 |
Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPY-02112 |
FGFR4 Protein, Human, Recombinant (His)
TKF,JTK2,CD334,fibroblast growth ... |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-04165 |
FGFR3 Protein, Human, Recombinant (His)
JTK4,CEK2,fibroblast growth f... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1. | |||
TMPY-00341 |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
CEK2,HSFGFR3EX,fibroblast growth ... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2. | |||
TMPY-03357 |
FGFR2 Protein, Mouse, Recombinant (hFc)
KGFR,AU043015,KGFRTr,Bek,Fgfr7,svs,fibroblast g... |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is AAA39377.1. | |||
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FG... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7. | |||
TMPY-06034 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL2,fib... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4. | |||
TMPY-01011 |
FGFR1 Protein, Human, Recombinant (His)
KAL2,FLT2,FGFBR,HRTFDS,OGD,FLG,HBGFR,bFGF-... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-00972 |
FGFR2 Protein, Human, Recombinant (His & hFc)
K-SAM,TK14,BBDS,fibroblast growth fact... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 α(III... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. | |||
TMPJ-00040 |
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G)
FGF-2,Fibroblast growth facto... |
Human | E. coli |
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P09038-2. | |||
TMPJ-00039 |
FGF-2 Protein, Human, Recombinant (K128N)
FGF2,bFGF,FGFB,Heparin-binding growth ... |
Human | E. coli |
FGF-2 Protein, Human, Recombinant (K128N) is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is P09038-2. | |||
TMPY-05473 |
KSP37/FGFBP2 Protein, Human, Recombinant (His)
HBP17RP,fibroblast growth factor ... |
Human | Baculovirus Insect Cells |
KSP37/FGFBP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9BYJ0. | |||
TMPY-06037 |
FGFR4 Protein, Human, Recombinant (His), Biotinylated
CD334,TKF,JTK2,fibroblast growth ... |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-00806 |
FGFR4 Protein, Human, Recombinant (hFc)
fibroblast growth factor receptor... |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1. | |||
TMPK-00847 |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 β (IIIb),KGFR,BEK,CD332,K-sam,FGFR-<... |
Mouse | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2. | |||
TMPK-00398 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPK-00399 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Keratinocyte growth factor receptor,K-sam,... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPK-00400 |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Fibroblast growth factor receptor... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3. | |||
TMPK-00397 |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
K-sam,CD332,KGFR,Keratinocyte growth f... |
Human | HEK293 Cells |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.2 kDa and the accession number is P21802-1. | |||
TMPK-00475 |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
K-sam,KSAM,KGFR,CD332,Keratinocyte growth ... |
Cynomolgus | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and the accession number is A0A2K5TL84-1. | |||
TMPJ-01312 |
TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)
Fibroblast growth factor-regulate... |
Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inf... | |||
TMPY-04200 |
FGFR3 Protein, Human, Recombinant (hFc)
CD333,HSFGFR3EX,CEK2,JTK4,fibroblast g... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is P22607-1. | |||
TMPY-00389 |
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
ACH,HSFGFR3EX,fibroblast growth factor... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is P22607-2. | |||
TMPY-00973 |
FGFR3 Protein, Mouse, Recombinant (His & hFc)
FR3,Fgfr-3,Flg-2,CD333,Mfr3,fibroblast |
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q7TSI8. | |||
TMPY-03389 |
FGFR2 Protein, Mouse, Recombinant (His)
svs,Fgfr-7,fibroblast growth factor |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1. | |||
TMPY-01208 |
FGFR3 Protein, Mouse, Recombinant (His)
fibroblast growth factor receptor... |
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is Q7TSI8. | |||
TMPY-01781 |
FGFR1 Protein, Mouse, Recombinant (His)
Flt-2,FLG,fibroblast growth f... |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number is P16092-1. | |||
TMPY-01782 |
FGFR1 Protein, Mouse, Recombinant (hFc)
Hspy,fibroblast growth factor rec... |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P16092-1. | |||
TMPY-06033 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
HBGFR,BFGFR,bFGF-R-1,FLG,FGFR-1,fibroblast grow... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,C... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7. | |||
TMPY-05777 |
FGFR1 Protein, Human, Recombinant (hFc)
N-SAM,OGD,HH2,HBGFR,FLT2,CEK,FLG,FGFR-1,FG... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number is NP_001341297.1. | |||
TMPY-04371 |
FGFR1 Protein, Human, Recombinant (His & GST)
HRTFDS,CEK,OGD,FLG,FLT2,FGFBR,bFGF-R-1,N-SAM,fi... |
Human | Baculovirus Insect Cells |
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is H9FRD4. | |||
TMPY-05761 |
FGFR1 Protein, Human, Recombinant (His), Biotinylated
FLT-2,KAL2,FGFBR,HRTFDS,BFGFR,fibrobla... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-00351 |
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
fibroblast growth factor receptor... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21. | |||
TMPY-01228 |
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
TK14,CEK3,BEK,BBDS,CD332,TK25,KGFR,BFR-1,<... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession number is P21802-1. | |||
TMPY-06321 |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
ECT1,CEK3,JWS,TK14,K-SAM,CD332,TK25,KGFR,<... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.88 kDa and the accession number is NP_075259.4. | |||
TMPY-04390 |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
CFD1,ECT1,K-SAM,BEK,KGFR,CD332,JWS,BFR-1,fibrob... |
Human | Baculovirus Insect Cells |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 kDa and the accession number is P21802-1. | |||
TMPY-04273 |
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TK25,ECT1,JWS,fibroblast growth <... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3. | |||
TMPY-05004 |
FGF-4 Protein, Human, Recombinant
HST-1,KFGF,fibroblast growth factor |
Human | E. coli |
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a... | |||
TMPY-02907 |
FGF-19 Protein, Human, Recombinant
fibroblast growth factor 19,FGF19 |
Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca... | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL-1F1,IL1-α,IL-1A,IL1F1,白细胞介素,IL-1 ... |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPY-02838 |
FGFBP3 Protein, Human, Recombinant (His)
C10orf13,FGF-BP3,fibroblast growth fac... |
Human | Baculovirus Insect Cells |
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are important regulators of cell migration, proliferation and differentiation, e.g., during embryogenesis and wound healing, and under several pathological conditions including tumor growth and tumor angiogenesis. Expression of FGF-BP increases after injury to murine and human skin, in p... | |||
TMPH-02135 |
SPRED1 Protein, Human, Recombinant (His & Myc & SUMO)
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Human | E. coli |
Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Attenuates actin stress fiber formation via inhibition of TESK1-mediated phosphorylation of cofilin. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells. SPRED1 Protein, Human, Reco... | |||
TMPH-02438 |
IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)
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Rhesus | E. coli |
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag... | |||
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